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Invitrogen™ QPRT Polyclonal Antibody
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Product Code. 17824550
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Quantity:
100 μL
Unit Size:
100µL
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17824550 100 μL 100µL
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Product Code. 17824550 Supplier Invitrogen™ Supplier No. PA5140031

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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: LLDNFKPEEL HPTATVLKAQ FPSVAVEASG GITLDNLPQF CGPHIDVISM GMLTQAAPAL DFSLKLFAKE VAPVPKI Highest antigen sequence indentity to the following orthologs: Rat - 78%, Mouse - 81%.

QPRT gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen QPRT
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene QPRT
Gene Accession No. Q15274
Gene Alias 2410027J01Rik; AI647766; epididymis secretory sperm binding protein Li 90n; HEL-S-90n; nicotinate-nucleotide pyrophosphorylase; nicotinate-nucleotide pyrophosphorylase (carboxylating); nicotinate-nucleotide pyrophosphorylase [carboxylating]; QAPRTase; QPRT; QPRTase; quinolinate phosphoribosyltransferase; Quinolinate phosphoribosyltransferase [decarboxylating]
Gene Symbols QPRT
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human QPRT. Recombinant protein control fragment (Product #RP-109525).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23475
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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