missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Culture Media, Supplements, and Reagents
  4. Cell Culture Reagents, Antibiotics and Supplements
  5. Antibiotics
  6. Thermo Scientific Chemicals (R,R)-Chloramphenicol, 98%

Thermo Scientific Chemicals (R,R)-Chloramphenicol, 98%

Product Code. 11455786
Change view
Click to view available options
Quantity:
25 g
100 g
Unit Size:
100g
25g
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity Unit Size
11455786 100 g 100g
11445786 25 g 25g
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Product Code. 11455786 Supplier Thermo Scientific Chemicals Supplier No. B20841.22
  • ONLINE EXCLUSIVE PRICE
    € 143.82
    € 122.65 / 100g
    Save € 21.17
    14% Off
View all promotions
 Restricted Item
In Stock
Add to basket
113.86 EUR valid until 2026-12-18
BEST PRICE on Promo! Use promo code "27967" to get your promotional price.

missing translation for 'validMainframeMsg'

Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

(R,R)-Chloramphenicol, CAS # 56-75-7, also known as chloromycetin, is a compound with broad-spectrum antibiotic and bacteriostatic activities. | CAS: 56-75-7 | C11H12Cl2N2O5 | 323.126 g/mol

Inhibitor of translation on the 50S subunit at the peptidyltransferase step. (R,R)-Chloramphenicol is widely utilized as an antibiotic, which is used for the treatment of number of bacterial infections and also act as a bacteriostatic. It is often used for bacterial selection in molecular biology applications. It also finds an application in ophthalmic and veterinary purposes. It also protects the mitochondrial and chloroplast protein synthesis and ribosomal formation of (p)ppGpp, de-pressing rRNA transcription.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • (R,R)-chloramphenicol is a compound with antibiotic and bacteriostatic activity and is derived from Streptomyces venequelae
  • It that can block the translation on the 50S subunit at the peptidyltransferase step. The binding affects the peptidyl transferase activity, preventing the transfer of amino acids to the growing peptide chains and inhibiting peptide bond formation. The resulting inhibition of the bacterial protein synthesis impedes bacterial cell proliferation

Application

  • (R,R)-chloramphenicol has been used for several molecular biology approaches, mainly for bacterial selection. It can be used to select transformed cells containing chloramphenicol resistance genes
  • This compound can also promote mitochondrial and chloroplast protein synthesis and the ribosomal formation of (p)ppGpp, depressing the rRNA transcription process
  • In vitro results demonstrate that (R,R)-chloramphenicol shows activity against several vancomycin-resistant E. faecium strains
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 56-75-7
Molecular Formula C11H12Cl2N2O5
Molecular Weight (g/mol) 323.126
MDL Number MFCD00078159
InChI Key WIIZWVCIJKGZOK-RKDXNWHRSA-N
Synonym Chloromycetin
PubChem CID 5959
ChEBI CHEBI:17698
IUPAC Name 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
SMILES C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]

Specifica

Type (R,R)-Chloramphenicol
Physical Form Crystalline Powder
Melting Point 149°C to 152°C
Color Cream to White
Quantity 100 g
Assay Percent Range 0.99
Beilstein 2225532
Merck Index 14,2077
Solubility Information Soluble in alcohol,propylene,glycol,acetone and ethyl acetate. Slightly soluble in water.
Formula Weight 323.14
Percent Purity ≥99%
Chemical Name or Material (R,R)-Chloramphenicol
Vedi altri risultati Mostra meno risultati

Sicurezza e movimentazione

compliance-icons
Identificativo prodotto
  • (R,R)-Chloramphenicol
 Avvertenza
  • Danger
 Categoria di pericolo
  • Carcinogenicity Category 1B
 Indicazioni di pericolo
  • H350-May cause cancer.
 Consigli di prudenza
  • P201-Obtain special instructions before use.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
 Informazioni supplementari
  • MIXTURE LIST-Contain: Chloramphenicol
SDS

RUO – Research Use Only

Titolo del prodotto
Selezionare un problema

Facendo clic su Invia, l'utente riconosce che potrebbe essere contattato da Fisher Scientific in merito al feedback fornito in questo modulo. Non condivideremo le vostre informazioni per altri scopi. Tutte le informazioni di contatto fornite saranno conservate in conformità con la nostra Politica sulla privacy. Informativa sulla privacy.