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RAB5A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. p-7203553 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16839353 20 μL 20µL
16829353 150 μL 150µL
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Product Code. 16839353 Supplier Proteintech Supplier No. 119471AP20UL

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Description

Rabbit Polyclonal Antibody

RAB5 are among the small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan. Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.

Specifications

Antigen RAB5A
Applications Immunofluorescence, Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunocytochemistry
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene RAB5A
Gene Accession No. M0RC99, P20339, Q9CQD1
Gene Alias RAB5, RAB5A, Ras related protein Rab 5A
Gene Symbols RAB5A
Host Species Rabbit
Immunogen RAB5A Fusion Protein Ag2549
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 271457, 5868, 64633
Target Species Rat, Mouse, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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