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Invitrogen™ RAB5C Polyclonal Antibody

Product Code. 16569481
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Quantity:
100 μL
Unit Size:
100µL
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16569481 100 μL 100µL
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Product Code. 16569481 Supplier Invitrogen™ Supplier No. PA596646

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAGRGGAARP NGPAAGNKIC QFKLVLLGES AVGKSSLVLR FVKGQFHEYQ ESTIGAAFLT QTVCLDDTTV KFEIWDTAGQ ERYHSLAPMY YRGAQAAIVV YDITNTDTFA RAKNWVKELQ RQASPNIVIA LAGNKADLAS KRAVEFQEAQ AYADDNSLLF METSAKTAMN VNEIFMAIAK KLPKNEPQNA TGAPGRNRGV DLQENNPASR SQCCSN; Positive Samples: A-549, BT-474, HL-60, Mouse lung; Cellular Location: Cell membrane, Cytoplasmic side, Early endosome membrane, Lipid-anchor, Melanosome.

The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAB5C
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.07 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RAB5C
Gene Accession No. P35278, P51148
Gene Alias AI326010; L1880; RAB; RAB5B; RAB5B, member RAS oncogene family; RAB5C; Rab5c protein; RAB5C, member of RAS oncogene family; RAB5C, member RAS oncogene family; RAB5C, member RAS oncogene family isoform b; RAB5CL; RAB5L; RABL; Ras-related protein Rab-5C; small GTPase; wu:fb98b08; wu:fi16g01
Gene Symbols RAB5C
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human RAB5C (NP_9588421).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19345, 287709, 5878
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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