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AGTR2 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of AGTR2.

Brand:  Abnova PAB16829.100ug

Product Code. 16042417

  • € 619.00 / 100µg

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Description

Description

Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G-protein coupled receptors. It is an integral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5kb. Exons 1 and 2 encode for 5' untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame. [provided by RefSeq]

Specifications

Specifications

AGTR2
Polyclonal
Rabbit polyclonal antibody raised against synthetic peptide of AGTR2.
In PBS (0.02% sodium azide)
AAS45437
AGTR2
A synthetic peptide corresponding to internal region 16 amino acids of human AGTR2.
RUO
186
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
ELISA, Immunohistochemistry, Western Blot
Unconjugated
Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
AGTR2
AT2/ATGR2/MRX88
Rabbit
100 μg
Primary
Human, Mouse, Rat
Liquid
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