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ALOX5 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Product Code. 16102620
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Quantity:
100 μg
Unit Size:
100µg
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16102620 100 μg 100µg
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Product Code. 16102620 Supplier Abnova Supplier No. PAB18083.100ug

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Description

Rabbit polyclonal antibody raised against synthetic peptide of ALOX5.

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq

Specifications

Antigen ALOX5
Applications ELISA, Immunohistochemistry, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of ALOX5.
Dilution Western Blot (1:500∼1:1000) Immunohistochemistry (1:50∼1:100) ELISA(1:10000) The optimal working dilution should be determined by the end user.
Formulation In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene ALOX5
Gene Accession No. P09917
Gene Alias 5-LO/5-LOX/5LPG/LOG5/MGC163204
Gene Symbols ALOX5
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues surrounding S271 of human ALOX5.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 240
Test Specificity This antibody is specific to ALOX5.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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