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Apolipoprotein E3, Rabbit, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against recombinant Apolipoprotein E3.
Brand: Abnova PAB19855.150ug
This item is not returnable.
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Description
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq
Specifications
| Apolipoprotein E3 | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against recombinant Apolipoprotein E3. | |
| In PBS, pH 7.5 (0.02% sodium azide, 50% glycerol (v/v)) | |
| AD2/LPG/MGC1571/apoprotein | |
| Rabbit | |
| Affinity purification | |
| RUO | |
| 348 | |
| Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| ELISA, Western Blot | |
| Unconjugated | |
| The optimal working dilution should be determined by the end user. | |
| APOE | |
| APOE | |
| Recombinant protein corresponding to human Apolipoprotein E3. | |
| 150 μg | |
| Primary | |
| Human | |
| Liquid |
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