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AR Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Product Code. 16060027
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
16060027 100 μg 100µg
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Product Code. 16060027 Supplier Abnova Supplier No. PAB12655.100ug

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Description

Rabbit polyclonal antibody raised against synthetic peptide of AR.

The androgen receptor gene is more than 90kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq

Specifications

Antigen AR
Applications ELISA, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of AR.
Dilution Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (2-5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In TBS, pH 7.2 (BSA, 10% Proclin300)
Gene AR
Gene Alias AIS/DHTR/HUMARA/KD/NR3C4/SBMA/SMAX1/TFM
Gene Symbols AR
Host Species Rabbit
Immunogen A synthetic peptide corresponding to N-terminus of human AR.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 367
Test Specificity This antibody recognizes ∼110 KDa of human AR.
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C. For long term storage store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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