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BMPR1B Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of BMPR1B.
Brand: Abnova PAB3839.400uL
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Description
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55kDa and type II receptors of about 70-80kDa. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. [provided by RefSeq
Specifications
| BMPR1B | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic peptide of BMPR1B. | |
| In PBS (0.09% sodium azide) | |
| NP_001194 | |
| BMPR1B | |
| A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human BMPR1B. | |
| 400 μL | |
| Primary | |
| Human, Mouse | |
| Liquid |
| ELISA, Western Blot | |
| Unconjugated | |
| Western Blot (1:1000) The optimal working dilution should be determined by the end user. | |
| BMPR1B | |
| ALK-6/ALK6/CDw293 | |
| Rabbit | |
| Protein G purification | |
| RUO | |
| 658 | |
| Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
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