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CBL (phospho Y700), Rabbit anti-Human, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic phosphopeptide of CBL.
Marca: Abnova PAB25918.100ug
Descripción
The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq
Sequence: T-E-Yp-M-TEspecificaciones
| CBL | |
| Polyclonal | |
| Unconjugated | |
| Immunohistochemistry (1:50-1:100) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user. | |
| CBL | |
| C-CBL/CBL2/RNF55 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 867 | |
| Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Immunofluorescence, Immunohistochemistry (PFA fixed) | |
| 1 mg/mL | |
| Rabbit polyclonal antibody raised against synthetic phosphopeptide of CBL. | |
| In PBS (without mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) | |
| P22681 | |
| CBL | |
| Synthetic phosphopeptide corresponding to residues surrounding Y700 of human CBL. | |
| 100 μg | |
| Primary | |
| Human | |
| Liquid |
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For Research Use Only