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CEACAM1 Rabbit anti-Human, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of CEACAM1.
Brand: Abnova PAB25597.50ug
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Description
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined. [provided by RefSeq
Specifications
| CEACAM1 | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic peptide of CEACAM1. | |
| In PBS (0.09% sodium azide) | |
| BGP/BGP1/BGPI | |
| Rabbit | |
| Immunoaffinity chromatography | |
| RUO | |
| 634 | |
| Human | |
| Liquid |
| Immunohistochemistry (PFA fixed) | |
| Unconjugated | |
| Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) The optimal working dilution should be determined by the end user. | |
| CEACAM1 | |
| CEACAM1 | |
| A synthetic peptide corresponding to 13 amino acids at internal region of human CEACAM1. | |
| 50 μg | |
| Primary | |
| BLAST analysis of the peptide immunogen showed no homology with other human proteins. | |
| Store at 4°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing. |
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