Learn More
CTNNB1 (phospho Y86), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic phosphopeptide of CTNNB1.
Brand: Abnova PAB7925.100uL
Description
Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM
Specifications
| CTNNB1 | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic phosphopeptide of CTNNB1. | |
| In PBS (50% glycerol, 1mg/mL BSA, 0.05% sodium azide) | |
| CTNNB/DKFZp686D02253/FLJ25606/FLJ37923 | |
| Rabbit | |
| 100 μL | |
| Primary | |
| This peptide sequence is highly conserved in rat and mouse beta-Catenin. | |
| Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| ELISA, Immunoprecipitation, Western Blot | |
| Unconjugated | |
| ELISA (1:2000) Western Blot (1:1000) The optimal working dilution should be determined by the end user. | |
| CTNNB1 | |
| CTNNB1 | |
| Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y86 of human CTNNB1. | |
| RUO | |
| 1499 | |
| Human, Mouse, Rat | |
| Liquid |
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
For Research Use Only