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CXCR2 Rabbit anti-Human, Rat, Polyclonal Antibody, Abnova™

Product Code. 16224500
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Quantity:
100 μg
Unit Size:
100µg
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16224500 100 μg 100µg
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Product Code. 16224500 Supplier Abnova Supplier No. PAB7969.100ug

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Description

Rabbit polyclonal antibody raised against synthetic peptide of CXCR2.

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq

Specifications

Antigen CXCR2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of CXCR2.
Dilution Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4 (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
Gene CXCR2
Gene Alias CD182/CDw128b/CMKAR2/IL8R2/IL8RA/IL8RB
Gene Symbols CXCR2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids at internal region of human CXCR2.
Purification Method Affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3579
Target Species Human, Rat
Content And Storage Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water and concentration will be 500μ/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
Isotype IgG
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