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DOK1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Product Code. 16169170
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Quantity:
100 μg
Unit Size:
100µg
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16169170 100 μg 100µg
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Product Code. 16169170 Supplier Abnova Supplier No. PAB5500.100ug

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Description

Rabbit polyclonal antibody raised against synthetic peptide of DOK1.

Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. [provided by RefSeq

Specifications

Antigen DOK1
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of DOK1.
Dilution Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene DOK1
Gene Alias MGC117395/MGC138860/P62DOK
Gene Symbols DOK1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues surrounding Y362 of human DOK1.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1796
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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