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EIF4EBP1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Product Code. 16052527
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Quantity:
100 μg
Unit Size:
100µg
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16052527 100 μg 100µg
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Product Code. 16052527 Supplier Abnova Supplier No. PAB16982.100ug

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Description

Rabbit polyclonal antibody raised against synthetic peptide of EIF4EBP1.

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq]

Specifications

Antigen EIF4EBP1
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of EIF4EBP1.
Dilution Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:20000) The optimal working dilution should be determined by the end user.
Formulation In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)
Gene EIF4EBP1
Gene Accession No. Q13541
Gene Alias 4E-BP1/4EBP1/BP-1/MGC4316/PHAS-I
Gene Symbols EIF4EBP1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues surrounding S65 of human EIF4EBP1.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1978
Test Specificity This antibody detects endogenous levels of total 4EBP1 protein.
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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