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EIF4EBP1 (phospho T70), Rabbit anti-Human, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human EIF4EBP1.
Marque: Abnova PAB29233.100uL
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Description
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq]
Spécification
| EIF4EBP1 | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic phosphopeptide of human EIF4EBP1. | |
| In PBS, pH 7.4 (without mg2+ and Ca2+), (50% glycerol, 0.02% sodium azide) | |
| Q13541 | |
| EIF4EBP1 | |
| Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T70 of human EIF4EBP1. | |
| 100 μL | |
| Primary | |
| This antibody detects endogenous levels of EIF4EBP1 only when phosphorylated at threonine 70. | |
| Store at -20°C. Avoid repeated freezing and thawing. |
| Immunohistochemistry (PFA fixed) | |
| Unconjugated | |
| Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user. | |
| EIF4EBP1 | |
| 4E-BP1/4EBP1/BP-1/MGC4316/PHAS-I | |
| Rabbit | |
| Affinity purification | |
| RUO | |
| 1978 | |
| Human | |
| Liquid |
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Nom du produit
For Research Use Only
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