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FANCD2 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against partial recombinant FANCD2.

Brand:  Abnova PAB12428.50uL

Product Code. 16029826

  • € 751.00 / 50µL

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Description

Description

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq

Specifications

Specifications

FANCD2
Polyclonal
Rabbit polyclonal antibody raised against partial recombinant FANCD2.
In Tris-glycine, 150mM NaCl (0.05% sodium azide)
Q9BXW9
FANCD2
Recombinant protein corresponding to N-terminus of human FANCD2.
RUO
2177
Human, Mouse
Liquid
Immunofluorescence, Immunohistochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Unconjugated
Immunofluorescence (1:200-1:500) Western Blot (1:10000-1:20000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5-5 ug/mL) The optimal working dilution should be determined by the end user.
FANCD2
DKFZp762A223/FA-D2/FA4/FACD/FAD/FAD2/FANCD/FLJ23826
Rabbit
50 μL
Primary
This antibody is specific to FANCD2.
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
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