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GJB6, Rabbit, Polyclonal Antibody, Abnova™

Product Code. 16008737
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Quantity:
400 μL
Unit Size:
400µL
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16008737 400 μL 400µL
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Product Code. 16008737 Supplier Abnova Supplier No. PAB3591.400uL

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Description

Rabbit polyclonal antibody raised against synthetic peptide of GJB6.

Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. [provided by RefSeq

Specifications

Antigen GJB6
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of GJB6.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene GJB6
Gene Accession No. O95452
Gene Alias CX30/DFNA3/ED2/EDH/HED
Gene Symbols GJB6
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human GJB6.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10804
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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