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IL7R Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of IL7R.

Brand:  Abnova PAB26934.100uL

Product Code. 16087107

  • € 503.00 / 100µL

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Description

Description

The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq

Specifications

Specifications

IL7R
Polyclonal
Unconjugated
Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
IL7R
IL7R
A synthetic peptide corresponding to human IL7R.
100 μL
Primary
IL7R polyclonal antibody detects endogenous levels of IL7R protein.
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Western Blot
1 mg/mL
Rabbit polyclonal antibody raised against synthetic peptide of IL7R.
In PBS, pH 7.2 (0.05% sodium azide)
CD127/CDW127/IL-7R-alpha/IL7RA/ILRA
Rabbit
Affinity purification
RUO
3575
Human, Mouse
Liquid
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