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LAT Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of LAT.
Brand: Abnova PAB17296.100ug
This item is not returnable.
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Description
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Specifications
| LAT | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic peptide of LAT. | |
| In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol) | |
| LAT1/pp36 | |
| Rabbit | |
| 100 μg | |
| Primary | |
| This antibody detects endogenous levels of total LAT protein. | |
| Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Western Blot | |
| Unconjugated | |
| Western Blot (1:500-1:1000) ELISA (1:5000) The optimal working dilution should be determined by the end user. | |
| LAT | |
| LAT | |
| A synthetic peptide corresponding to residues surrounding serine 363 of human LAT. | |
| RUO | |
| 27040 | |
| Human, Mouse | |
| Liquid |
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