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LCK (phospho Y505), Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of LCK.

Brand:  Abnova PAB12750.100ug

Product Code. 16030127

  • € 406.00 / 100µg

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Description

Description

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq

Specifications

Specifications

LCK
Polyclonal
Rabbit polyclonal antibody raised against synthetic phosphopeptide of LCK.
In TBS, pH 7.2 (BSA, 10% Proclin300)
YT16/p56lck/pp58lck
Rabbit
100 μg
Primary
This antibody recognizes LCK with a phosphorylated site of Tyrosine 505. It does not cross-react with non-phosphospecific peptide.
Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Unconjugated
Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) The optimal working dilution should be determined by the end user.
LCK
LCK
Synthetic phosphopeptide corresponding to residues surrounding Y505 of human, rat, bovine and dog LCK.
RUO
3932
Bovine, Canine, Human, Mouse, Rat
Liquid
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