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LCK (phospho Y505), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic phosphopeptide of LCK.
Brand: Abnova PAB14161.100uL
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Description
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq
Sequence: GQYpQPSpecifications
| LCK | |
| Polyclonal | |
| Unconjugated | |
| Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user. | |
| LCK | |
| LCK | |
| Synthetic phosphopeptide corresponding to residues surrounding Y505 of human LCK. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| Rabbit polyclonal antibody raised against synthetic phosphopeptide of LCK. | |
| In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) | |
| YT16/p56lck/pp58lck | |
| Rabbit | |
| Immunoaffinity purification | |
| RUO | |
| 3932 | |
| Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
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