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MAP2K4 (phospho T261), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Description
This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. [provided by RefSeq
Specifications
Specifications
| Antigen | MAP2K4 |
| Applications | Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic phosphopeptide of MAP2K4. |
| Dilution | Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) |
| Gene | MAP2K4 |
| Gene Alias | JNKK/JNKK1/MAPKK4/MEK4/MKK4/PRKMK4/SEK1/SERK1 |
| Gene Symbols | MAP2K4 |
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