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MMP13 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Description
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
Specifications
Specifications
| Antigen | MMP13 |
| Applications | ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of MMP13. |
| Dilution | Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (1:100) The optimal working dilution should be determined by the end user. |
| Formulation | In TBS, pH 7.2 (BSA, 10% Proclin300) |
| Gene | MMP13 |
| Gene Alias | CLG3 |
| Gene Symbols | MMP13 |
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For Research Use Only
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