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NFKBIA Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Product Code. 16038956
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Quantity:
200 μg
Unit Size:
200µg
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16038956 200 μg 200µg
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Product Code. 16038956 Supplier Abnova Supplier No. PAB0870.200ug

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Description

Rabbit polyclonal antibody raised against a synthetic peptide of NFKBIA.

NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM

Specifications

Antigen NFKBIA
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against a synthetic peptide of NFKBIA.
Dilution Western Blot (1:200) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.2% gelatin, 0.09% sodium azide)
Gene NFKBIA
Gene Alias IKBA/MAD-3/NFKBI
Gene Symbols NFKBIA
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human NFKBIA.
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4792
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
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