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NFKBIA Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of NFKBIA.

Brand:  Abnova PAB4345.400uL

Product Code. 16049027

  • € 384.00 / 400µL

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Description

Description

NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM

Specifications

Specifications

NFKBIA
Polyclonal
Rabbit polyclonal antibody raised against synthetic peptide of NFKBIA.
In PBS (0.09% sodium azide)
IKBA/MAD-3/NFKBI
Rabbit
Protein G purification
RUO
4792
Human
Liquid
ELISA, Western Blot
Unconjugated
ELISA (1:1000) Western Blot (1:100-500) The optimal working dilution should be determined by the end user.
NFKBIA
NFKBIA
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human NFKBIA.
400 μL
Primary
This antibody recognize synthetic peptide corresponding to sumoylation site of human NFKBIA.
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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