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NLRC4 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Product Code. 16000237
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Quantity:
100 μg
Unit Size:
100µg
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16000237 100 μg 100µg
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Product Code. 16000237 Supplier Abnova Supplier No. PAB12895.100ug

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Description

Rabbit polyclonal antibody raised against synthetic peptide of NLRC4.

In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM

Specifications

Antigen NLRC4
Applications Immunocytochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of NLRC4.
Dilution Western Blot (0.5-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.02% sodium azide)
Gene NLRC4
Gene Alias CARD12/CLAN/CLAN1/CLANA/CLANB/CLANC/CLAND/CLR2.1/IPAF
Gene Symbols NLRC4
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus of human NLRC4.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58484
Test Specificity A 110 KDa band can be detected. Ipaf antibody is human specific.
Target Species Human
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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