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OGDH Rabbit anti-Human, Polyclonal Antibody, Abnova™
Description
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms
Specifications
Specifications
| Antigen | OGDH |
| Applications | Immunofluorescence, Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against recombinant OGDH. |
| Dilution | Immunohistochemistry (1:20-1:50) Immunofluorescence (1-4 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.5 (40% glycerol, 0.02% sodium azide) |
| Gene | OGDH |
| Gene Alias | AKGDH/E1k/OGDC |
| Gene Symbols | OGDH |
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For Research Use Only
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