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PLA2R1 Rabbit anti-Human, Polyclonal Antibody, Abnova™
Description
Secretory phospholipases A2 (PLA2s) have been purified from a variety of mammalian tissues as well as from insect and snake venoms. The prototype group I PLA2, the pancreatic PLA2 (PLA2G1B; MIM 172410), is involved in digestion, smooth muscle contraction, and cell proliferation. The prototype group II PLA2, the inflammatory-type PLA2 (PLA2G2A; MIM 172411), is involved in inflammatory conditions and is upregulated by proinflammatory cytokines like tumor necrosis factor (TNF; MIM 191160) and interleukin-1 (e.g., IL1B; MIM 147720). Differential toxicity of snake venom Pla2 appears to be linked to a variety of high-affinity receptors in different organs (Ancian et al., 1995 [PubMed 7721806]).[supplied by OMIM
Specifications
Specifications
| Antigen | PLA2R1 |
| Applications | Immunohistochemistry, Immunohistochemistry (Formalin/Paraffin) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against recombinant PLA2R1 |
| Dilution | Immunohistochemistry (1:500-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.2, (40% glycerol, 0.02% sodium azide) |
| Gene | PLA2R1 |
| Gene Alias | CLEC13C/PLA2-R/PLA2G1R/PLA2IR/PLA2R |
| Gene Symbols | PLA2R1 |
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For Research Use Only
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