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PRDM16, Rabbit, Polyclonal Antibody, Abnova™

Product Code. 16033717
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Quantity:
100 μg
Unit Size:
100µg
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16033717 100 μg 100µg
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Product Code. 16033717 Supplier Abnova Supplier No. PAB19171.100ug

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Description

Rabbit polyclonal antibody rasied against synthetic peptide of PRDM16.

The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq

Specifications

Antigen PRDM16
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody rasied against synthetic peptide of PRDM16.
Dilution Western blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.02% sodium azide)
Gene PRDM16
Gene Accession No. CAH71530
Gene Alias KIAA1675/MEL1/MGC166915/PFM13
Gene Symbols PRDM16
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 17 amino acids near C-terminus of human PRDM16.
Purification Method Affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 63976
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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