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PRKCZ Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Product Code. 16139180
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Quantity:
100 μg
Unit Size:
100µg
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16139180 100 μg 100µg
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Product Code. 16139180 Supplier Abnova Supplier No. PAB5521.100ug

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Description

Rabbit polyclonal antibody raised against synthetic peptide of PRKCZ.

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq

Specifications

Antigen PRKCZ
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PRKCZ.
Dilution Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
Formulation In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene PRKCZ
Gene Alias PKC-ZETA/PKC2
Gene Symbols PRKCZ
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues surrounding T410 of human PRKCZ.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5590
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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