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PSMC4, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against recombinant PSMC4.

Brand:  Abnova PAB28661.100uL

Product Code. 16146930

  • € 619.00 / 100µL

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Description

Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 nonidentical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a nonlysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with an orphan member of the nuclear hormone receptor superfamily highly expressed in liver, and with gankyrin, a liver oncoprotein. Two transcript variants encoding different isoforms have been identified. [provided by RefSeq

Sequence: LEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNA
Specifications

Specifications

PSMC4
Polyclonal
Rabbit polyclonal antibody raised against recombinant PSMC4.
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
MGC13687/MGC23214/MGC8570/MIP224/S6/TBP7
Rabbit
Antigen affinity purification
RUO
5704
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
IgG
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(1:200-1:500) Immunofluorescence (1-4 ug/ml) The optimal working dilution should be determined by the end user.
PSMC4
PSMC4
Recombinant protein corresponding to amino acids of human PSMC4.
100 μL
Primary
Human, Mouse, Rat
Liquid
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