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PTGS1 Rabbit anti-Human, Rat, Sheep, Polyclonal Antibody, Abnova™

Product Code. 16030817
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Quantity:
50 μL
Unit Size:
50µL
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16030817 50 μL 50µL
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Product Code. 16030817 Supplier Abnova Supplier No. PAB13621.50uL

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Description

Rabbit polyclonal antibody raised against synthetic peptide of PTGS1.

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. [provided by RefSeq

Specifications

Antigen PTGS1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PTGS1.
Dilution Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Formulation In buffer containing 0.01% sodium azide
Gene PTGS1
Gene Alias COX1/COX3/PCOX1/PGG/HS/PGHS-1/PGHS1/PHS1/PTGHS
Gene Symbols PTGS1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to PTGS1.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5742
Test Specificity The polyclonal antibody with the highest specificity for Prostaglandin H Synthase 1 (PGHS-1), also known as Cyclooxygenase 1 (COX-1) and corresponds to a sequence region unique to COX-1. This antibody reacts with native, as well as, recombinant COX-1 from several species including human, sheep, rat and most other mammalian species, except mouse. It does not cross-react with COX-2 from any of the species examined to date.
Target Species Human, Rat, Sheep
Content And Storage Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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