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RB1 (phospho S807), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Product Code. 16095587
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Quantity:
100 μg
Unit Size:
100µg
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16095587 100 μg 100µg
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Product Code. 16095587 Supplier Abnova Supplier No. PAB25408.100ug

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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of RB1.

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq

Sequence: Y-I-Sp-P-L

Specifications

Antigen RB1
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of RB1.
Dilution Western Blot (1:500-1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene RB1
Gene Alias OSRC/RB/p105-Rb/pRb/pp110
Gene Symbols RB1
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding S807 of human RB1.
Purification Method Affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5925
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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