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RNF7 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Product Code. 16059126
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Quantity:
100 μL
Unit Size:
100µL
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16059126 100 μL 100µL
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Product Code. 16059126 Supplier Abnova Supplier No. PAB10234.100uL

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Rabbit polyclonal antibody raised against synthetic peptide of RNF7.

The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Specifications

Antigen RNF7
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of RNF7.
Dilution ELISA (1:2000-1:10000) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
Formulation In antiserum (0.01% sodium azide)
Gene RNF7
Gene Alias CKBBP1/ROC2/SAG
Gene Symbols RNF7
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to amino acids 102-113 of human RNF7.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9616
Test Specificity Cross reactivity may also occur with ROC2 from other sources. Sufficient sequence differences exist to suggest that this antibody would not react with other RING box proteins such as ROC1 and APC11.
Target Species Human, Mouse
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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