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SERPINE1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Product Code. 16081317
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1 mL
Unit Size:
1mL
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Product Code. 16081317 Supplier Abnova Supplier No. PAB14897.1mL

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Description

Rabbit polyclonal antibody raised against native SERPINE1.

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen SERPINE1
Applications ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Immunoprecipitation, Inhibition Assays, Radioimmune Assays (RIA), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against native SERPINE1.
Dilution The optimal working dilution should be determined by the end user.
Formulation In serum
Gene SERPINE1
Gene Alias PAI/PAI-1/PAI1/PLANH1
Gene Symbols SERPINE1
Host Species Rabbit
Immunogen Native purified human SERPINE1 from the HT 1080 fibrosarcoma cell line.
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5054
Test Specificity This antibody reacts with human PAI-1s from endothelial cells. No reactivity with human PAI-2. Identity established by double diffusion with human PAI-1 isolated from human endothelial cells (HUVEC) culture and recombinant PAI-1 expressed in E.coli. No other proteins so far tested showed greater than 1% cross reaction.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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