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SPHK1 Rabbit anti-Human, Monkey, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of SPHK1.
Brand: Abnova PAB16316.50ug
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Description
Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM
Specifications
| SPHK1 | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic peptide of SPHK1. | |
| In PBS (0.09% sodium azide) | |
| SPHK | |
| Rabbit | |
| Immunoaffinity purification | |
| RUO | |
| 8877 | |
| Human, Monkey | |
| Liquid |
| Immunohistochemistry (PFA fixed) | |
| Unconjugated | |
| Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) The optimal working dilution should be determined by the end user. | |
| SPHK1 | |
| SPHK1 | |
| A synthetic peptide (conjugated with KLH) corresponding to human SPHK1. | |
| 50 μg | |
| Primary | |
| N-terminal domain of human. | |
| Store at 4°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing. |
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