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SSRP1 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against full-length recombinant SSRP1.
Marca: Abnova PAB10372.100ug
Descrizione
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq
Specifica
| SSRP1 | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against full length recombinant SSRP1. | |
| In PBS (0.08% sodium azide) | |
| FACT/FACT80/T160 | |
| Rabbit | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| Unconjugated | |
| Western blot (5 to 10 ug/mL) The optimal working dilution should be determined by the end user. | |
| SSRP1 | |
| SSRP1 | |
| Recombinant His fusion protein corresponding to full length SSRP1. | |
| RUO | |
| 6749 | |
| Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
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