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SSRP1 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Product Code. 16089226
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Quantity:
100 μg
Unit Size:
100µg
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16089226 100 μg 100µg
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Product Code. 16089226 Supplier Abnova Supplier No. PAB10373.100ug

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Description

Rabbit polyclonal antibody raised against partial recombinant SSRP1.

The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq

Specifications

Antigen SSRP1
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against partial recombinant SSRP1.
Dilution Western blot (5 to 10 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.08% sodium azide)
Gene SSRP1
Gene Alias FACT/FACT80/T160
Gene Symbols SSRP1
Host Species Rabbit
Immunogen Recombinant protein corresponding to amino acids 1-242 of human SSRP1.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6749
Target Species Human, Mouse
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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