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STAT3 (phospho Y705), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic phosphopeptide of STAT3.
Brand: Abnova PAB24732.100uL
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Description
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Specifications
| STAT3 | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic phosphopeptide of STAT3. | |
| In PBS, pH 7.2 (0.09% sodium azide) | |
| APRF/FLJ20882/HIES/MGC16063 | |
| Rabbit | |
| Antigen affinity purification | |
| RUO | |
| 6774 | |
| Human, Mouse | |
| Liquid |
| Western Blot | |
| Unconjugated | |
| Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user. | |
| STAT3 | |
| STAT3 | |
| Synthetic phosphopeptide corresponding to residues surrounding Y705 of STAT3. | |
| 100 μL | |
| Primary | |
| STAT3 (phospho Y705) polyclonal antibody detects endogenous levels of STAT3 protein. | |
| Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
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