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TP73 (phospho Y99), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Product Code. 16189230
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Quantity:
100 μg
Unit Size:
100µg
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16189230 100 μg 100µg
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Product Code. 16189230 Supplier Abnova Supplier No. PAB5789.100ug

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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of TP73.

This gene encodes tumor protein p73, which is a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53, p63, and p73 and have high sequence similarity to one another, which allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways involving direct or indirect protein interactions, resulting in regulation of the same target gene promoters or regulation of each other's promoters. The p73 protein is expressed at very low levels in normal tissues and is differentially expressed in a number of tumors. The p73 gene expresses at least 35 mRNA variants due to the use of alternate promoters, alternate translation initiation sites, and multiple splice variations. Theoretically this can account for 29 different p73 isoforms; however, the biological validity and the full-length nature of most variants have not been determined. [provided by RefSeq]

Specifications

Antigen TP73
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of TP73.
Dilution Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene TP73
Gene Alias P73
Gene Symbols TP73
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding Y99 of human TP73.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7161
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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