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XRCC4, Rabbit, Polyclonal Antibody, Abnova™
Description
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by nonhomologous end joining and the completion of V(D)J recombination events. The nonhomologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq
Specifications
Specifications
| Antigen | XRCC4 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of XRCC4. |
| Dilution | Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In 1X PBS, pH 7.2 (0.05% sodium azide) |
| Gene | XRCC4 |
| Gene Symbols | XRCC4 |
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For Research Use Only
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