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Invitrogen™ RAD21 Monoclonal Antibody (CM110-2C10)

Description
In Western blot, two bands are seen: the full-length Rad21 is seen around 130 kDa, while the cleaved Rad21 is seen around 70 kDa. Suggested positive control: antigen standard for RAD21 (transient overexpression lysate), Hela whole cell extract.
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.
Specifications
Specifications
| Antigen | RAD21 |
| Applications | Western Blot |
| Classification | Monoclonal |
| Clone | CM110-2C10 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.1% sodium azide |
| Gene | Rad21 |
| Gene Accession No. | O60216, Q61550 |
| Gene Alias | 64-kDa carboxy-terminal product; 64-kDa C-terminal product; 65-kDa carboxy-terminal product; CDLS4; double-strand-break repair protein rad21 homolog; double-strand-break repair protein rad21-like protein; FLJ25655; FLJ40596; h NXP-1; hHR21; HR21; HRAD21; KIAA0078; KIAA0078RAD21; kleisin; MCD1; mHR21; mKIAA0078; nuclear matrix protein 1; NXP1; NXP-1; Pokeweed agglutinin-binding protein 29; protein involved in DNA double-strand break repair; PW29; Rad21; RAD21 cohesin complex component; RAD21 homolog; RAD21 homolog (S. pombe); SCC1; SCC1 homolog; sister chromatid cohesion 1 |
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