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RAD23B Monoclonal Antibody (OTI13A2), TrueMAB™, OriGene

Product Code. 17524673
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100 μL
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17524673 100 μL 100µL
17544673 30 μL 30µL
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Product Code. 17524673 Supplier Origene Technologies Supplier No. TA804896

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Description

Mouse Monoclonal Antibody

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Specifications

Antigen RAD23B
Applications Western Blot
Classification Monoclonal
Clone OTI13A2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene RAD23B
Gene Accession No. P54727
Gene Alias HHR23B, HR23B, P58
Gene Symbols RAD23B
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 1-253 of human RAD23B produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5887
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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