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RAD23B Mouse anti-Human, Clone: OTI13A3, lyophilized, TrueMAB™

Código de producto. 17608191
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Quantity:
100 μg
Tamaño de la unidad:
100µg
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Código de producto. 17608191 Proveedor Origene Technologies N.º de proveedor CF804864

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Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Especificaciones

Antigen RAD23B
Applications Western Blot
Classification Monoclonal
Clone OTI13A3
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene RAD23B
Gene Accession No. P54727
Gene Alias HHR23B, HR23B, P58
Gene Symbols RAD23B
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 1-253 of human RAD23B produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5887
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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