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Invitrogen™ RAD23B Polyclonal Antibody
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Product Code. 15724151 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15724151 100 μL 100µL
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Product Code. 15724151 Supplier Invitrogen™ Supplier No. PA556237

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LPALLQQIGR ENPQLLQQIS QHQEHFIQML NEPVQEAGGQ GGGGGGGSGG IAEAGSGHMN YIQVTPQE Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 91%.

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAD23B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Rad23b
Gene Accession No. P54727
Gene Alias 0610007D13Rik; AV001138; HHR23B; HR23B; Mhr23b; P58; RAD23 homolog B (S. cerevisiae); RAD23 homolog B, nucleotide excision repair protein; RAD23, yeast homolog of, B; RAD23B; RAD23b homolog; RAD23b homolog (S. cerevisiae); UV excision repair protein RAD23 homolog B; XP-C repair complementing complex 58 kDa; XP-C repair complementing protein; XP-C repair-complementing complex 58 kDa protein
Gene Symbols Rad23b
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RAD23B. Recombinant protein control fragment (Product #RP-95283).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5887
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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