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  6. Invitrogen™ RAD50 Recombinant Rabbit Monoclonal Antibody (K01_2P20)

Invitrogen™ RAD50 Recombinant Rabbit Monoclonal Antibody (K01_2P20)
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Product Code. 30829264
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30829264 100 μL
30828926 50 μL
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Product Code. 30829264 Supplier Invitrogen™ Supplier No. MA564185

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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: MSRIEKMSIL GVRSFGIEDK DKQIITFFSP LTILVGPNGA GKTTIIECLK YICTGDFPPG TKGNTFVHDP KVAQETDVRA QIRLQFRDVN GELIAVQRSM VCTQKSKKTE FKTLEGVITR TKHGEKVSLS SKCAEIDREM ISSLGVSKAV LNNVIFCHQE DSNWPLSEGK ALKQKFDEIF SATRYIKALE TLRQVRQTQG QKVKEYQMEL KYLKQYKEKA CEIRDQITSK EAQLTSSKEI VKSYENELDP LKNRLKEIEH NLSKIMKLDN EIKALDSRKK QMEKDNSELE EKMEKVFQGT DEQLNDLYHN HQRTVREKER KLVDCHRELE KLNKESRLLN QEKSELLVEQ GRLQLQADRH QEHIRARDSL IQSLATQLEL DGFERGPFSE RQIKNFHKLV RERQEGEAKT ANQLMNDFAE KETLK Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%, Pig - 95%, Cynomolgus monkey - 100%.

Rad50-13B3 recognizes human Rad50, a 153a protein involved in DNA double strand break repair. Rad50 is associated with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, Rad50 and Mre11 redistribute and are co-localized within the nucleus of damaged cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RAD50
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone K01_2P20
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 40% glycerol, 150mM NaCl, 0.05% BSA and 0.01% sodium azide; pH 7.4
Gene RAD50
Gene Accession No. Q92878
Gene Alias 153 kDa protein; DNA repair protein RAD50; hRad50; hsRAD50; I79_004319; mRad50; Mrell; MRX complex DNA-binding subunit; N0872; NBSLD; Rad50; RAD50 2; RAD50 double strand break repair protein; RAD50 homolog (S. cerevisiae); RAD50 homolog, double strand break repair protein; RAD50 PEN; RAD502; RAD50-2; RAD50-3; Rad50l; YNL250W
Gene Symbols RAD50
Host Species Rabbit
Immunogen Recombinant protein of human Rad50 (aa 1-425).
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10111
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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