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Invitrogen™ RAD51 Monoclonal Antibody (14B4)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA123271
This item is not returnable.
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Description
A suggested positive control for this product is T24.
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recobination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Mutations in the gene can results in breast cancer, mirror movements 2 and fanconi anemia.
Specifications
| RAD51 | |
| Monoclonal | |
| 1.0 mg/mL | |
| PBS with no preservative; pH 7 | |
| P37383, Q06609, Q08297 | |
| Rad51 | |
| Full length (amino acids 1-338) Rad51 expressed in E. coli. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat, Chicken | |
| Antibody | |
| IgG2a |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Proximity Ligation Assay, Immunocytochemistry | |
| 14B4 | |
| Unconjugated | |
| Rad51 | |
| AV304093; BRCA1/BRCA2-containing complex, subunit 5; BRCC5; DNA repair protein RAD51; DNA repair protein RAD51 homolog 1; DNA repair protein RAD51 homolog A; DNA repair protein rhp51; FANCR; homolog to S.cerevisiae; HRAD51; HsRad51; HsT16930; MGC128559 protein; MRMV2; MUT5; rad51; RAD51 homolog; RAD51 homolog (RecA homolog); RAD51 homolog (RecA homolog, E. coli); RAD51 homolog A; RAD51 recombinase; RAD51 recombinase L homeolog; rad51.1; rad51.L; rad51-1; RAD51A; rad51-a; rad51-b; Reca; RecA family recombinase Rhp51; RecA, E. coli, homolog of; RecA-like protein; recombinase RAD51; recombination protein A; RGD1563603; rhp51; SPAC644.14c; wu:fb38e12; xrad51; XRad51.1; YER095W; zgc:77754 | |
| Mouse | |
| Antigen affinity chromatography | |
| RUO | |
| 19361, 396086, 499870, 5888 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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