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Beskrivning
DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. Double-strand breaks are generally thought to be repaired via one of two distinct mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ). Homologous recombination requires the activity of the members of the RAD52 epistasis group, which includeRAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2. RAD52 can catalyze strand annealing reactions, and can form oligomers that attach to ends of single-stranded DNA.
Specifikationer
Specifikationer
| Antigen | RAD52 |
| Applications | Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.4 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gene | RAD52 |
| Gene Accession No. | P43351 |
| Gene Alias | RAD52, RAD52 homolog (S. cerevisiae) |
| Gene Symbols | RAD52 |
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Produkttitel
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