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RALA Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16821944 Shop All Proteintech Products
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150 μL
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20µL
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16821944 20 μL 20µL
16811944 150 μL 150µL
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Product Code. 16821944 Supplier Proteintech Supplier No. 136291AP20UL

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Rabbit Polyclonal Antibody

Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.

Specifications

Antigen RALA
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RALA
Gene Accession No. P11233, P63321, P63322
Gene Alias RAL, RALA, Ras related protein Ral A
Gene Symbols RALA
Host Species Rabbit
Immunogen RALA Fusion Protein Ag4547
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56044, 5898, 81757
Target Species Mouse, Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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